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Determination of the obesity-associated gene variants within the entire FTO gene by ultra-deep targeted sequencing in obese and lean children

BACKGROUND: The Fat mass and obesity-associated gene (FTO) was the first gene reliably associated with body mass index in genome-wide association studies on a population level. At present, the genetic variations within the FTO gene are still the common variants that have the largest influence on bod...

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Detalles Bibliográficos
Autores principales: Sällman Almén, M, Rask-Andersen, M, Jacobsson, J A, Ameur, A, Kalnina, I, Moschonis, G, Juhlin, S, Bringeland, N, Hedberg, L A, Ignatovica, V, Chrousos, G P, Manios, Y, Klovins, J, Marcus, C, Gyllensten, U, Fredriksson, R, Schiöth, H B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595467/
https://www.ncbi.nlm.nih.gov/pubmed/22531089
http://dx.doi.org/10.1038/ijo.2012.57