Concentration- and schedule-dependent effects of chemotherapy on the angiogenic potential and drug sensitivity of vascular endothelial cells

The anti-angiogenic activity of chemotherapy is both dose- and schedule-dependent. While conventional maximum tolerated dose (MTD) chemotherapy exerts only mild and reversible anti-angiogenic effects, low-dose metronomic (LDM) chemotherapy was developed to specifically target tumour angiogenesis. Ho...

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Detalles Bibliográficos
Autores principales: Pasquier, Eddy, Tuset, Maria-Pia, Street, Janine, Sinnappan, Snega, MacKenzie, Karen L., Braguer, Diane, Andre, Nicolas, Kavallaris, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2012
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595478/
https://www.ncbi.nlm.nih.gov/pubmed/23143659
http://dx.doi.org/10.1007/s10456-012-9321-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595478/
https://www.ncbi.nlm.nih.gov/pubmed/23143659
http://dx.doi.org/10.1007/s10456-012-9321-x

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