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The DNA damage checkpoint response to replication stress: A Game of Forks

Conditions challenging replication fork progression, collectively referred to as replication stress, represent a major source of genomic instability and are associated to cancer onset. The replication checkpoint, a specialized branch of the DNA damage checkpoint, monitors fork problems, and triggers...

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Detalles Bibliográficos
Autores principales: Jossen, Rachel, Bermejo, Rodrigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595514/
https://www.ncbi.nlm.nih.gov/pubmed/23493417
http://dx.doi.org/10.3389/fgene.2013.00026