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The DNA damage checkpoint response to replication stress: A Game of Forks
Conditions challenging replication fork progression, collectively referred to as replication stress, represent a major source of genomic instability and are associated to cancer onset. The replication checkpoint, a specialized branch of the DNA damage checkpoint, monitors fork problems, and triggers...
Autores principales: | Jossen, Rachel, Bermejo, Rodrigo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595514/ https://www.ncbi.nlm.nih.gov/pubmed/23493417 http://dx.doi.org/10.3389/fgene.2013.00026 |
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