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Curcumin targets fibroblast–tumor cell interactions in oral squamous cell carcinoma

Co-culture of periodontal ligament fibroblasts (PDLs) and SCC-25 oral squamous carcinoma cells (OSCC) results in conversion of PDLs into carcinoma-associated fibroblasts (CAFs) and induces epithelial-to mesenchymal transition (EMT) of OSCC tumor cells. We hypothesized that Curcumin targets this dyna...

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Detalles Bibliográficos
Autores principales: Dudás, József, Fullár, Alexandra, Romani, Angela, Pritz, Christian, Kovalszky, Ilona, Hans Schartinger, Volker, Mathias Sprinzl, Georg, Riechelmann, Herbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595529/
https://www.ncbi.nlm.nih.gov/pubmed/23247073
http://dx.doi.org/10.1016/j.yexcr.2012.12.001