Cargando…
Role of EZH2 in Epithelial Ovarian Cancer: From Biological Insights to Therapeutic Target
EZH2 is the catalytic subunit of polycomb repressive complex 2 (PRC2), which generates a methylation epigenetic mark at lysine 27 residue of histone H3 (H3K27me3) to silence gene expression. EZH2 target genes are involved in a variety of biological processes such as stem cell pluripotency, cell prol...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2013
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595978/ https://www.ncbi.nlm.nih.gov/pubmed/23494175 http://dx.doi.org/10.3389/fonc.2013.00047 |