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Parthenolide attenuates LPS-induced activation of NF-κB in a time-dependent manner in rat myocardium()

Parthenolide (PTN), a selective nuclear factor kappa B (NF-κB) inhibitor, has been used extensively to inhibit NF-κB activation. The duration of the inhibitory effect of PTN on NF-κB in vivo remains unclear. This study was to determine whether a lipopolysaccharide (LPS) challenge 6, 12 and 24 h afte...

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Detalles Bibliográficos
Autores principales: Xie, Hong, Wang, Chen, Wu, Xuemei, Liu, Xia, Qiao, Shigang, Liu, Chunfeng, Liu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596078/
https://www.ncbi.nlm.nih.gov/pubmed/23554728
http://dx.doi.org/10.1016/S1674-8301(12)60005-0