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Mge1, a nucleotide exchange factor of Hsp70, acts as an oxidative sensor to regulate mitochondrial Hsp70 function

Despite the growing evidence of the role of oxidative stress in disease, its molecular mechanism of action remains poorly understood. The yeast Saccharomyces cerevisiae provides a valuable model system in which to elucidate the effects of oxidative stress on mitochondria in higher eukaryotes. Dimeri...

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Detalles Bibliográficos
Autores principales: Marada, Adinarayana, Allu, Praveen Kumar, Murari, Anjaneyulu, PullaReddy, BhoomiReddy, Tammineni, Prasad, Thiriveedi, Venkata Ramana, Danduprolu, Jayasree, Sepuri, Naresh Babu V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596242/
https://www.ncbi.nlm.nih.gov/pubmed/23345595
http://dx.doi.org/10.1091/mbc.E12-10-0719