Cargando…

Myosin phosphatase is inactivated by caspase-3 cleavage and phosphorylation of myosin phosphatase targeting subunit 1 during apoptosis

In nonapoptotic cells, the phosphorylation level of myosin II is constantly maintained by myosin kinases and myosin phosphatase. During apoptosis, caspase-3–activated Rho-associated protein kinase I triggers hyperphosphorylation of myosin II, leading to membrane blebbing. Although inhibition of myos...

Descripción completa

Detalles Bibliográficos
Autores principales:	Iwasaki, Takahiro, Katayama, Takeshi, Kohama, Kazuhiro, Endo, Yaeta, Sawasaki, Tatsuya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2013
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596246/ https://www.ncbi.nlm.nih.gov/pubmed/23345589 http://dx.doi.org/10.1091/mbc.E11-08-0740

Ejemplares similares

Association of the Myosin-binding Subunit of Myosin Phosphatase and Moesin: Dual Regulation of Moesin Phosphorylation by Rho-associated Kinase and Myosin Phosphatase
por: Fukata, Yuko, et al.
Publicado: (1998)

Phosphorylation of Myosin-Binding Subunit (Mbs) of Myosin Phosphatase by Rho-Kinase in Vivo
por: Kawano, Yoji, et al.
Publicado: (1999)

Activation of Myosin Phosphatase Targeting Subunit by Mitosis-specific Phosphorylation
por: Totsukawa, Go, et al.
Publicado: (1999)

Phosphorylated Peptide Derived from the Myosin Phosphatase Target Subunit Is a Novel Inhibitor of Protein Phosphatase-1
por: Kónya, Zoltán, et al.
Publicado: (2023)

Protein Phosphatase 1 β Paralogs Encode the Zebrafish Myosin Phosphatase Catalytic Subunit
por: Jayashankar, Vaishali, et al.
Publicado: (2013)

Myosin light chain kinase and myosin light chain phosphatase from Dictyostelium: effects of reversible phosphorylation on myosin structure and function
Publicado: (1987)

Interaction of Myosin Phosphatase Target Subunit (MYPT1) with Myosin Phosphatase-RhoA Interacting Protein (MRIP): A Role of Glutamic Acids in the Interaction
por: Lee, Eunhee, et al.
Publicado: (2015)

Myosin light chain phosphatase catalytic subunit dephosphorylates cardiac myosin via mechanisms dependent and independent of the MYPT regulatory subunits
por: Lee, Eunyoung, et al.
Publicado: (2022)

Interplay of myosin phosphatase and protein phosphatase-2A in the regulation of endothelial nitric-oxide synthase phosphorylation and nitric oxide production
por: Bátori, Róbert, et al.
Publicado: (2017)

Par-4: A New Activator of Myosin Phosphatase
por: Vetterkind, Susanne, et al.
Publicado: (2010)

Biotinylated-sortase self-cleavage purification (BISOP) method for cell-free produced proteins
por: Matsunaga, Satoko, et al.
Publicado: (2010)

Phasic contractions of isolated human myometrium are associated with Rho-kinase (ROCK)-dependent phosphorylation of myosin phosphatase-targeting subunit (MYPT1)
por: Hudson, Claire A., et al.
Publicado: (2012)

Reconstituted Human Myosin Light Chain Phosphatase Reveals Distinct Roles of Two Inhibitory Phosphorylation Sites of the Regulatory Subunit, MYPT1
por: Khasnis, Mukta, et al.
Publicado: (2014)

TIMAP inhibits endothelial myosin light chain phosphatase by competing with MYPT1 for the catalytic protein phosphatase 1 subunit PP1cβ
por: Wang, Xin, et al.
Publicado: (2019)

Stress-Inducible Caspase Substrate TRB3 Promotes Nuclear Translocation of Procaspase-3
por: Shimizu, Kouhei, et al.
Publicado: (2012)

Calcium inhibition as an intracellular signal for actin–myosin interaction
por: KOHAMA, Kazuhiro
Publicado: (2016)

Overexpression of Myosin Phosphatase Target Subunit 1 (MYPT1) Inhibits Tumor Progression and Metastasis of Gastric Cancer
por: Wang, Fengyong, et al.
Publicado: (2018)

Moesin and myosin phosphatase confine neutrophil orientation in a chemotactic gradient
por: Liu, Xiaowen, et al.
Publicado: (2015)

Myosin phosphatase Fine-tunes Zebrafish Motoneuron Position during Axonogenesis
por: Bremer, Juliane, et al.
Publicado: (2016)

Myosin Phosphatase Is Implicated in the Control of THP-1 Monocyte to Macrophage Differentiation
por: Tóth, Emese, et al.
Publicado: (2021)

Myosin : Subunits and their interactions
por: Dreizen, Paul, et al.
Publicado: (1967)

Myosin light-chain phosphatase regulates basal actomyosin oscillations during morphogenesis
por: Valencia-Expósito, Andrea, et al.
Publicado: (2016)

Acute glucose influx-induced mitochondrial hyperpolarization inactivates myosin phosphatase as a novel mechanism of vascular smooth muscle contraction
por: Xu, Jie, et al.
Publicado: (2021)

p90 ribosomal S6 kinase (RSK) phosphorylates myosin phosphatase and thereby controls edge dynamics during cell migration
por: Samson, Shiela C., et al.
Publicado: (2019)

cGMP effects on vascular tone: modulating the activity of myosin light chain phosphatase
por: Brozovich, Frank V
Publicado: (2009)

Effects of a Fluorescent Myosin Light Chain Phosphatase Inhibitor on Prostate Cancer Cells
por: Grindrod, Scott, et al.
Publicado: (2011)

Regulation of Myosin Light-Chain Phosphatase Activity to Generate Airway Smooth Muscle Hypercontractility
por: Álvarez-Santos, Mayra D., et al.
Publicado: (2020)

Attenuated platelet aggregation in patients with septic shock is independent from the activity state of myosin light chain phosphorylation or a reduction in Rho kinase-dependent inhibition of myosin light chain phosphatase
por: Reddi, Benjamin AJ, et al.
Publicado: (2015)

Epigallocatechine-3-gallate Inhibits the Adipogenesis of Human Mesenchymal Stem Cells via the Regulation of Protein Phosphatase-2A and Myosin Phosphatase
por: Bécsi, Bálint, et al.
Publicado: (2022)

Assembly of Smooth Muscle Myosin by the 38k Protein, a Homologue of a Subunit of Pre-mRNA Splicing Factor-2
por: Okagaki, Tsuyoshi, et al.
Publicado: (2000)

Decreased Phosphatase Activity, Increased Ca(2+) Sensitivity, and Myosin Light Chain Phosphorylation in Urinary Bladder Smooth Muscle of Newborn Mice
por: Ekman, Mari, et al.
Publicado: (2005)

Altered Expression of Human Smooth Muscle Myosin Phosphatase Targeting (MYPT) Isovariants with Pregnancy and Labor
por: Lartey, Jon, et al.
Publicado: (2016)

Phosphatase regulatory subunit MYPT2 knockout partially compensates for the cardiac dysfunction in mice caused by lack of myosin light chain kinase 3
por: Hu, Tingfei, et al.
Publicado: (2023)

Production and partial purification of membrane proteins using a liposome-supplemented wheat cell-free translation system
por: Nozawa, Akira, et al.
Publicado: (2011)

Protein phosphatase type-1, not type-2A, modulates actin microfilament integrity and myosin light chain phosphorylation in living nonmuscle cells
Publicado: (1990)

Unfair competition governs the interaction of pCPI-17 with myosin phosphatase (PP1-MYPT1)
por: Filter, Joshua J, et al.
Publicado: (2017)

Phosphorylation of myosin regulatory light chain controls myosin head conformation in cardiac muscle
por: Kampourakis, Thomas, et al.
Publicado: (2015)

Lipid Emulsion Inhibits Vasodilation Induced by a Toxic Dose of Bupivacaine via Attenuated Dephosphorylation of Myosin Phosphatase Target Subunit 1 in Isolated Rat Aorta
por: Ok, Seong-Ho, et al.
Publicado: (2015)

Simple Screening Method for Autoantigen Proteins Using the N-Terminal Biotinylated Protein Library Produced by Wheat Cell-Free Synthesis
por: Matsuoka, Kazuhiro, et al.
Publicado: (2010)

Smoothelin-like 1 deletion enhances myogenic reactivity of mesenteric arteries with alterations in PKC and myosin phosphatase signaling
por: Turner, Sara R., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_vnfbeph39avaequnrpeu5eh10c