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Rab25 regulates integrin expression in polarized colonic epithelial cells

Rab25 is a tumor suppressor for colon cancer in humans and mice. To identify elements of intestinal polarity regulated by Rab25, we developed Caco2-BBE cell lines stably expressing short hairpin RNA for Rab25 and lines rescuing Rab25 knockdown with reexpression of rabbit Rab25. Rab25 knockdown decre...

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Detalles Bibliográficos
Autores principales: Krishnan, Moorthy, Lapierre, Lynne A., Knowles, Byron C., Goldenring, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596252/
https://www.ncbi.nlm.nih.gov/pubmed/23345591
http://dx.doi.org/10.1091/mbc.E12-10-0745