TORC1-regulated protein kinase Npr1 phosphorylates Orm to stimulate complex sphingolipid synthesis

The evolutionarily conserved Orm1 and Orm2 proteins mediate sphingolipid homeostasis. However, the homologous Orm proteins and the signaling pathways modulating their phosphorylation and function are incompletely characterized. Here we demonstrate that inhibition of nutrient-sensitive target of rapa...

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Detalles Bibliográficos
Autores principales: Shimobayashi, Mitsugu, Oppliger, Wolfgang, Moes, Suzette, Jenö, Paul, Hall, Michael N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596256/
https://www.ncbi.nlm.nih.gov/pubmed/23363605
http://dx.doi.org/10.1091/mbc.E12-10-0753

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596256/
https://www.ncbi.nlm.nih.gov/pubmed/23363605
http://dx.doi.org/10.1091/mbc.E12-10-0753

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