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Quantitative FRET Imaging to Visualize the Invasiveness of Live Breast Cancer Cells

Matrix metalloproteinases (MMPs) remodel tumor microenvironment and promote cancer metastasis. Among the MMP family proteases, the proteolytic activity of the pro-tumorigenic and pro-metastatic membrane-type 1 (MT1)-MMP constitutes a promising and targetable biomarker of aggressive cancer tumors. In...

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Detalles Bibliográficos
Autores principales: Lu, Shaoying, Wang, Yi, Huang, He, Pan, Yijia, Chaney, Eric J., Boppart, Stephen A., Ozer, Howard, Strongin, Alex Y., Wang, Yingxiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596289/
https://www.ncbi.nlm.nih.gov/pubmed/23516511
http://dx.doi.org/10.1371/journal.pone.0058569