Inhibition of Rho and Rac Geranylgeranylation by Atorvastatin Is Critical for Preservation of Endothelial Junction Integrity

BACKGROUND: Small GTPases (guanosine triphosphate, GTP) are involved in many critical cellular processes, including inflammation, proliferation, and migration. GTP loading and isoprenylation are two important post-translational modifications of small GTPases, and are critical for their normal functi...

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Detalles Bibliográficos
Autores principales: Xiao, Hongbing, Qin, Xiong, Ping, Ding, Zuo, Keqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596292/
https://www.ncbi.nlm.nih.gov/pubmed/23555637
http://dx.doi.org/10.1371/journal.pone.0059233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596292/
https://www.ncbi.nlm.nih.gov/pubmed/23555637
http://dx.doi.org/10.1371/journal.pone.0059233

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