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NOA36 Protein Contains a Highly Conserved Nucleolar Localization Signal Capable of Directing Functional Proteins to the Nucleolus, in Mammalian Cells

NOA36/ZNF330 is an evolutionarily well-preserved protein present in the nucleolus and mitochondria of mammalian cells. We have previously reported that the pro-apoptotic activity of this protein is mediated by a characteristic cysteine-rich domain. We now demonstrate that the nucleolar localization...

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Detalles Bibliográficos
Autores principales: de Melo, Ivan S., Jimenez-Nuñez, Maria D., Iglesias, Concepción, Campos-Caro, Antonio, Moreno-Sanchez, David, Ruiz, Felix A., Bolívar, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596294/
https://www.ncbi.nlm.nih.gov/pubmed/23516598
http://dx.doi.org/10.1371/journal.pone.0059065