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The Landscape of Host Transcriptional Response Programs Commonly Perturbed by Bacterial Pathogens: Towards Host-Oriented Broad-Spectrum Drug Targets

BACKGROUND: The emergence of drug-resistant pathogen strains and new infectious agents pose major challenges to public health. A promising approach to combat these problems is to target the host’s genes or proteins, especially to discover targets that are effective against multiple pathogens, i.e.,...

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Detalles Bibliográficos
Autores principales: Kidane, Yared H., Lawrence, Christopher, Murali, T. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596304/
https://www.ncbi.nlm.nih.gov/pubmed/23516507
http://dx.doi.org/10.1371/journal.pone.0058553