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A Unified Conformational Selection and Induced Fit Approach to Protein-Peptide Docking

Protein-peptide interactions are vital for the cell. They mediate, inhibit or serve as structural components in nearly 40% of all macromolecular interactions, and are often associated with diseases, making them interesting leads for protein drug design. In recent years, large-scale technologies have...

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Detalles Bibliográficos
Autores principales: Trellet, Mikael, Melquiond, Adrien S. J., Bonvin, Alexandre M. J. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596317/
https://www.ncbi.nlm.nih.gov/pubmed/23516555
http://dx.doi.org/10.1371/journal.pone.0058769