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A Unified Conformational Selection and Induced Fit Approach to Protein-Peptide Docking
Protein-peptide interactions are vital for the cell. They mediate, inhibit or serve as structural components in nearly 40% of all macromolecular interactions, and are often associated with diseases, making them interesting leads for protein drug design. In recent years, large-scale technologies have...
Autores principales: | Trellet, Mikael, Melquiond, Adrien S. J., Bonvin, Alexandre M. J. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596317/ https://www.ncbi.nlm.nih.gov/pubmed/23516555 http://dx.doi.org/10.1371/journal.pone.0058769 |
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