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Insulin-Stimulated Degradation of Apolipoprotein B100: Roles of Class II Phosphatidylinositol-3-Kinase and Autophagy

Both in humans and animal models, an acute increase in plasma insulin levels, typically following meals, leads to transient depression of hepatic secretion of very low density lipoproteins (VLDL). One contributing mechanism for the decrease in VLDL secretion is enhanced degradation of apolipoprotein...

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Detalles Bibliográficos
Autores principales: Andreo, Ursula, Guo, Liang, Chirieac, Doru V., Tuyama, Ana C., Montenont, Emilie, Brodsky, Jeffrey L., Fisher, Edward A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596368/
https://www.ncbi.nlm.nih.gov/pubmed/23516411
http://dx.doi.org/10.1371/journal.pone.0057590