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Klotho Endows Hepatoma Cells with Resistance to Anoikis via VEGFR2/PAK1 Activation in Hepatocellular Carcinoma

Klotho was originally characterized as an aging suppressor gene that predisposed Klotho-deficient mice to premature aging-like syndrome. Although Klotho was recently reported to exhibit tumor suppressive properties during various malignant transformations, the functional role and molecular mechanism...

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Detalles Bibliográficos
Autores principales: Chen, Lin, Liu, Haiou, Liu, Jing, Zhu, Yu, Xu, Le, He, Hongyong, Zhang, Heng, Wang, Shanshan, Wu, Qian, Liu, Weisi, Liu, Yidong, Pan, Deng, Ren, Shifang, Xu, Jiejie, Gu, Jianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596390/
https://www.ncbi.nlm.nih.gov/pubmed/23516476
http://dx.doi.org/10.1371/journal.pone.0058413