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CYP17 T27C polymorphism and prostate cancer risk: a meta-analysis based on 31 studies

OBJECTIVE: The cytochrome P450 17α-hydroxylase (CYP17) plays a vital role in androgen biosynthesis. A T-to-C polymorphism in the 5′ promoter region of CYP17 has been implicated as a risk factor for prostate cancer, but the results of individual studies are inconclusive or controversial. To derive a...

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Detalles Bibliográficos
Autores principales: Wei, Bingbing, Zhang, Yunyun, Xi, Bo, Chang, Junkai, Bai, Jinming, Su, Jiantang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596559/
https://www.ncbi.nlm.nih.gov/pubmed/23554635
http://dx.doi.org/10.1016/S1674-8301(10)60033-4