Iptakalim, a novel ATP-sensitive potassium channel opener, inhibits pulmonary arterial smooth muscle cell proliferation by downregulation of PKC-α()

Iptakalim is a new ATP-sensitive potassium (K(ATP)) channel opener, and it inhibits the proliferation of pulmonary arterial smooth muscle cells (PASMCs) and pulmonary vascular remodeling. However, the underlying mechanism remains unclear. In the present study, we found that iptakalim significantly d...

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Detalles Bibliográficos
Autores principales: Zuo, Xiangrong, Zong, Feng, Wang, Hui, Wang, Qiang, Xie, Weiping, Wang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2011
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596718/
https://www.ncbi.nlm.nih.gov/pubmed/23554716
http://dx.doi.org/10.1016/S1674-8301(11)60052-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596718/
https://www.ncbi.nlm.nih.gov/pubmed/23554716
http://dx.doi.org/10.1016/S1674-8301(11)60052-3

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