Cargando…

53BP1 facilitates long-range DNA end-joining during V(D)J recombination

V(D)J recombination and class switch recombination employ overlapping but distinct non-homologous end-joining (NHEJ) pathways to repair DNA double strand break (DSB) intermediates. 53BP1 is a DNA damage response protein that is rapidly recruited to sites of chromosomal DSBs, where it appears to func...

Descripción completa

Detalles Bibliográficos
Autores principales: Difilippantonio, Simone, Gapud, Eric, Wong, Nancy, Huang, Ching-Yu, Mahowald, Grace, Chen, Hua Tang, Kruhlak, Michael J., Livak, Ferenc, Nussenzweig, Michel, Sleckman, Barry P., Nussenzweig, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596817/
https://www.ncbi.nlm.nih.gov/pubmed/18931658
http://dx.doi.org/10.1038/nature07476