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Phosphoinositide-3-kinases p110α and p110β mediate S phase entry in astroglial cells in the marginal zone of rat neocortex

In cells cultured from neocortex of newborn rats, phosphoinositide-3-kinases of class I regulate the DNA synthesis in a subgroup of astroglial cells. We have studied the location of these cells as well as the kinase isoforms which facilitate the S phase entry. Using dominant negative (dn) isoforms a...

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Detalles Bibliográficos
Autores principales: Müller, Rabea, Fischer, Catharina, Wilmes, Thomas, Heimrich, Bernd, Distel, Vanessa, Klugbauer, Norbert, Meyer, Dieter K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596864/
https://www.ncbi.nlm.nih.gov/pubmed/23504389
http://dx.doi.org/10.3389/fncel.2013.00024