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Combined Effects of PPARγ Agonists and Epidermal Growth Factor Receptor Inhibitors in Human Proximal Tubule Cells

We aimed to determine whether epidermal growth factor receptor (EGFR) inhibition, in addition to a peroxisome proliferator-activated receptor gamma (PPARγ) agonist, prevents high-glucose-induced proximal tubular fibrosis, inflammation, and sodium and water retention in human proximal tubule cells ex...

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Detalles Bibliográficos
Autores principales: Pegg, Katherine, Zhang, Jie, Pollock, Carol, Saad, Sonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596915/
https://www.ncbi.nlm.nih.gov/pubmed/23533381
http://dx.doi.org/10.1155/2013/982462