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Palmitoylethanolamide Is a Disease-Modifying Agent in Peripheral Neuropathy: Pain Relief and Neuroprotection Share a PPAR-Alpha-Mediated Mechanism

Neuropathic syndromes which are evoked by lesions to the peripheral or central nervous system are extremely difficult to treat, and available drugs rarely joint an antihyperalgesic with a neurorestorative effect. N-Palmitoylethanolamine (PEA) exerts antinociceptive effects in several animal models a...

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Detalles Bibliográficos
Autores principales: Di Cesare Mannelli, L., D'Agostino, G., Pacini, A., Russo, R., Zanardelli, M., Ghelardini, C., Calignano, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596927/
https://www.ncbi.nlm.nih.gov/pubmed/23533304
http://dx.doi.org/10.1155/2013/328797