Clinical Application of Sleeping Beauty and Artificial Antigen Presenting Cells to Genetically Modify T Cells from Peripheral and Umbilical Cord Blood

The potency of clinical-grade T cells can be improved by combining gene therapy with immunotherapy to engineer a biologic product with the potential for superior (i) recognition of tumor-associated antigens (TAAs), (ii) persistence after infusion, (iii) potential for migration to tumor sites, and (i...

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Detalles Bibliográficos
Autores principales: Huls, M. Helen, Figliola, Matthew J., Dawson, Margaret J., Olivares, Simon, Kebriaei, Partow, Shpall, Elizabeth J., Champlin, Richard E., Singh, Harjeet, Cooper, Laurence J.N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2013
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596954/
https://www.ncbi.nlm.nih.gov/pubmed/23407473
http://dx.doi.org/10.3791/50070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596954/
https://www.ncbi.nlm.nih.gov/pubmed/23407473
http://dx.doi.org/10.3791/50070

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