Single-cell gene expression profiling reveals functional heterogeneity of undifferentiated human epidermal cells

Human epidermal stem cells express high levels of β1 integrins, delta-like 1 (DLL1) and the EGFR antagonist LRIG1. However, there is cell-to-cell variation in the relative abundance of DLL1 and LRIG1 mRNA transcripts. Single-cell global gene expression profiling showed that undifferentiated cells fe...

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Detalles Bibliográficos
Autores principales: Tan, David W. M., Jensen, Kim B., Trotter, Matthew W. B., Connelly, John T., Broad, Simon, Watt, Fiona M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Company of Biologists 2013
Materias:
Development and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596987/
https://www.ncbi.nlm.nih.gov/pubmed/23482486
http://dx.doi.org/10.1242/dev.087551

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596987/
https://www.ncbi.nlm.nih.gov/pubmed/23482486
http://dx.doi.org/10.1242/dev.087551

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