An intronic ncRNA-dependent regulation of SORL1 expression affecting Aβ formation is upregulated in post-mortem Alzheimer's disease brain samples

Recent studies indicated that sortilin-related receptor 1 (SORL1) is a risk gene for late-onset Alzheimer's disease (AD), although its role in the aetiology and/or progression of this disorder is not fully understood. Here, we report the finding of a non-coding (nc) RNA (hereafter referred to a...

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Detalles Bibliográficos
Autores principales: Ciarlo, Eleonora, Massone, Sara, Penna, Ilaria, Nizzari, Mario, Gigoni, Arianna, Dieci, Giorgio, Russo, Claudio, Florio, Tullio, Cancedda, Ranieri, Pagano, Aldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2013
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597024/
https://www.ncbi.nlm.nih.gov/pubmed/22996644
http://dx.doi.org/10.1242/dmm.009761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597024/
https://www.ncbi.nlm.nih.gov/pubmed/22996644
http://dx.doi.org/10.1242/dmm.009761

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