Obesity improves myocardial ischaemic tolerance and RISK signalling in insulin-insensitive rats

Obesity with associated metabolic disturbances worsens ischaemic heart disease outcomes, and rodent studies confirm that obesity with insulin-resistance impairs myocardial resistance to ischemia-reperfusion (I-R) injury. However, the effects of obesity per se are unclear, with some evidence for para...

Descripción completa

Detalles Bibliográficos
Autores principales: Donner, Daniel, Headrick, John P., Peart, Jason N., du Toit, Eugene F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597027/
https://www.ncbi.nlm.nih.gov/pubmed/23161371
http://dx.doi.org/10.1242/dmm.010959

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597027/
https://www.ncbi.nlm.nih.gov/pubmed/23161371
http://dx.doi.org/10.1242/dmm.010959

Ejemplares similares