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Obesity improves myocardial ischaemic tolerance and RISK signalling in insulin-insensitive rats
Obesity with associated metabolic disturbances worsens ischaemic heart disease outcomes, and rodent studies confirm that obesity with insulin-resistance impairs myocardial resistance to ischemia-reperfusion (I-R) injury. However, the effects of obesity per se are unclear, with some evidence for para...
Autores principales: | Donner, Daniel, Headrick, John P., Peart, Jason N., du Toit, Eugene F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Limited
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597027/ https://www.ncbi.nlm.nih.gov/pubmed/23161371 http://dx.doi.org/10.1242/dmm.010959 |
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