Cargando…

Structural basis for duplex RNA recognition and cleavage by Archaeoglobus fulgidus C3PO

Oligomeric complexes of Trax and Translin proteins, known as C3POs, participate in a variety of eukaryotic nucleic acid metabolism pathways including RNAi and tRNA processing. In RNAi in humans and Drosophila, C3PO activates pre-RISC by removing the passenger strand of the siRNA precursor duplex usi...

Descripción completa

Detalles Bibliográficos
Autores principales: Parizotto, Eneida A, Lowe, Edward D, Parker, James S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597040/
https://www.ncbi.nlm.nih.gov/pubmed/23353787
http://dx.doi.org/10.1038/nsmb.2487