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Structural basis for duplex RNA recognition and cleavage by Archaeoglobus fulgidus C3PO
Oligomeric complexes of Trax and Translin proteins, known as C3POs, participate in a variety of eukaryotic nucleic acid metabolism pathways including RNAi and tRNA processing. In RNAi in humans and Drosophila, C3PO activates pre-RISC by removing the passenger strand of the siRNA precursor duplex usi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597040/ https://www.ncbi.nlm.nih.gov/pubmed/23353787 http://dx.doi.org/10.1038/nsmb.2487 |