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Sinomenine reduces iNOS expression via inhibiting the T-bet IFN-γ pathway in experimental autoimmune encephalomyelitis in rats

Sinomenine is a bioactive alkaloid isolated from the Chinese medicinal plant Sinomenium acutum. It is widely used as an immunosuppressive drug for treating rheumatic and arthritic diseases. In our previous studies, we found that sinomenine reduced cellular infiltration within the spinal cord and all...

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Detalles Bibliográficos
Autores principales: Gu, Bingjie, Zeng, Yanying, Yin, Cheng, Wang, Huijiuan, Yang, Xiaofan, Wang, Song, Ji, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597047/
https://www.ncbi.nlm.nih.gov/pubmed/23554784
http://dx.doi.org/10.7555/JBR.26.20110114