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Sinomenine reduces iNOS expression via inhibiting the T-bet IFN-γ pathway in experimental autoimmune encephalomyelitis in rats
Sinomenine is a bioactive alkaloid isolated from the Chinese medicinal plant Sinomenium acutum. It is widely used as an immunosuppressive drug for treating rheumatic and arthritic diseases. In our previous studies, we found that sinomenine reduced cellular infiltration within the spinal cord and all...
Autores principales: | Gu, Bingjie, Zeng, Yanying, Yin, Cheng, Wang, Huijiuan, Yang, Xiaofan, Wang, Song, Ji, Xiaohui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Editorial Department of Journal of Biomedical Research
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597047/ https://www.ncbi.nlm.nih.gov/pubmed/23554784 http://dx.doi.org/10.7555/JBR.26.20110114 |
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