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Cellular exposure to muscle relaxants and propofol could lead to genomic instability in vitro

Anesthesia is widely used in several medical settings and accepted as safe. However, there is some evidence that anesthetic agents can induce genomic changes leading to neural degeneration or apoptosis. Although chromosomal changes have not been observed in vivo, this is most likely due to DNA repai...

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Detalles Bibliográficos
Autores principales: Coleman, Allen Edward, McNeil, Nicole, Kovalchuck, Alexander Leonidovich, Wangsa, Dara, Ried, Thomas, Wang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597328/
https://www.ncbi.nlm.nih.gov/pubmed/23554740
http://dx.doi.org/10.1016/S1674-8301(12)60021-9