Cargando…

Cellular exposure to muscle relaxants and propofol could lead to genomic instability in vitro

Anesthesia is widely used in several medical settings and accepted as safe. However, there is some evidence that anesthetic agents can induce genomic changes leading to neural degeneration or apoptosis. Although chromosomal changes have not been observed in vivo, this is most likely due to DNA repai...

Descripción completa

Detalles Bibliográficos
Autores principales:	Coleman, Allen Edward, McNeil, Nicole, Kovalchuck, Alexander Leonidovich, Wangsa, Dara, Ried, Thomas, Wang, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Editorial Department of Journal of Biomedical Research 2012
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597328/ https://www.ncbi.nlm.nih.gov/pubmed/23554740 http://dx.doi.org/10.1016/S1674-8301(12)60021-9

Ejemplares similares

Concurrent V(D)J recombination and DNA end instability increase interchromosomal trans-rearrangements in ATM-deficient thymocytes
por: Bowen, Steven, et al.
Publicado: (2013)

The Relaxant Effect of Propofol on Isolated Rat Intrapulmonary Arteries
por: Zhang, Guangyan, et al.
Publicado: (2014)

Genomic instability influences the transcriptome and proteome in endometrial cancer subtypes
por: Habermann, Jens K, et al.
Publicado: (2011)

Evaluation of Intubating Conditions with Varying Doses of Propofol without Muscle Relaxants
por: Gore, Mangesh S, et al.
Publicado: (2011)

Lead Exposure Induces Telomere Instability in Human Cells
por: Pottier, Géraldine, et al.
Publicado: (2013)

A case report: instability after distal humerus hemiarthroplasty leading to revision with a total elbow arthroplasty
por: McNeil, Daniel S., et al.
Publicado: (2023)

Transtracheal lidocaine: An alternative to intraoperative propofol infusion when muscle relaxants are not used
por: Rajan, Sunil, et al.
Publicado: (2014)

Lysosomes relax in the cellular suburbs
por: Gowrishankar, Swetha, et al.
Publicado: (2016)

Thermalization and relaxation mediated by phonon management in tin-lead perovskites
por: Dai, Linjie, et al.
Publicado: (2023)

Endotracheal intubation without muscle relaxants in children using remifentanil and propofol: Comparative study
por: Naziri, Freshteh, et al.
Publicado: (2015)

Bipolar disorder dynamics: affective instabilities, relaxation oscillations and noise
por: Bonsall, Michael B., et al.
Publicado: (2015)

Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability
por: Akagi, Keiko, et al.
Publicado: (2014)

TP53 loss initiates chromosomal instability in fallopian tube epithelial cells
por: Bronder, Daniel, et al.
Publicado: (2021)

Effect of Benson’s Relaxation Technique on Propofol Consumption and Preoperative Anxiety of Patients Undergoing Cataract Surgery
por: Barabady, Afsaneh, et al.
Publicado: (2020)

Comparative Evaluation between Sevoflurane and Propofol for Endotracheal Intubation without Muscle Relaxants in Pediatric Cleft Surgeries
por: Karanth, Harish, et al.
Publicado: (2018)

Where Could Research on Immunosenescence Lead?
por: De la Fuente, Mónica
Publicado: (2019)

Blast Exposure Leads to Accelerated Cellular Senescence in the Rat Brain
por: Arun, Peethambaran, et al.
Publicado: (2020)

Feasibility and Safety of Remazolam versus Propofol When Inserting Laryngeal Masks Without Muscle Relaxants During Hysteroscopy
por: Tang, Shan, et al.
Publicado: (2023)

Relaxation methods
por: De Garrs, Allen Deryck Norman
Publicado: (1954)

Europe could steal a nuclear lead
por: Parkinson, R
Publicado: (1970)

Talar and Subtalar T1ρ Relaxation Times in Limbs with and without Chronic Ankle Instability
por: Song, Kyeongtak, et al.
Publicado: (2021)

The effect of muscle length on transcranial magnetic stimulation‐induced relaxation rate in the plantar flexors
por: Yacyshyn, Alexandra F., et al.
Publicado: (2017)

Lead Exposure Can Affect Early Childhood Development and Could Be Aggravated by Stunted Growth: Perspectives from Mexico
por: Córdoba-Gamboa, Leonel, et al.
Publicado: (2023)

Characterisation of breast fine-needle aspiration biopsies by centrosome aberrations and genomic instability
por: Kronenwett, U, et al.
Publicado: (2005)

Cigarette smoking leads to reduced relaxant responses of the cutaneous microcirculation
por: Edvinsson, Marie-Louise, et al.
Publicado: (2008)

Relax, it's only uncertainty: lead the way when the way is changing
por: Hodgson, Philip, et al.
Publicado: (2020)

Muscle relaxant induced pancreatitis leading to hyperosmolar hyperglycemic state
por: Bao, Yicheng K, et al.
Publicado: (2019)

Repeated stress exposure leads to structural synaptic instability prior to disorganization of hippocampal coding and impairments in learning
por: Chenani, Alireza, et al.
Publicado: (2022)

Independent Mechanisms Lead to Genomic Instability in Hodgkin Lymphoma: Microsatellite or Chromosomal Instability †
por: Cuceu, Corina, et al.
Publicado: (2018)

Using fentanyl and propofol for tracheal intubation during sevoflurane induction without muscle relaxants in children: A randomized prospective study
por: Abdelhalim, Ashraf Arafat, et al.
Publicado: (2017)

Downregulation of connexin 43-based gap junctions underlies propofol-induced excessive relaxation in hypertensive vascular smooth muscle cells
por: Zeng, Weiqi, et al.
Publicado: (2023)

Propofol TCI or sevoflurane anesthesia without muscle relaxant for thoracoscopic thymectomy in myasthenia gravis patients: a prospective, observational study
por: Hien, Vo Van, et al.
Publicado: (2023)

How could stress lead to major depressive disorder?
por: Richter-Levin, Gal, et al.
Publicado: (2018)

COVID-19: How the quarantine could lead to the depreobesity
por: Mediouni, Mohamed, et al.
Publicado: (2020)

Antiviral Efficacy of the Anesthetic Propofol against Dengue Virus Infection and Cellular Inflammation
por: Shen, Ting-Jing, et al.
Publicado: (2021)

Single Chromosome Aneuploidy Induces Genome-Wide Perturbation of Nuclear Organization and Gene Expression
por: Braun, Rüdiger, et al.
Publicado: (2019)

Can Propofol Lead to an Increase in Seizure Threshold Over the Course of Electroconvulsive Therapy?
por: Aytuluk, Hande Gurbuz, et al.
Publicado: (2019)

Propofol Pharmacokinetics and Estimation of Fetal Propofol Exposure during Mid-Gestational Fetal Surgery: A Maternal-Fetal Sheep Model
por: Ngamprasertwong, Pornswan, et al.
Publicado: (2016)

A Novel Cellular Defect in Diabetes: Membrane Repair Failure
por: Howard, Amber C., et al.
Publicado: (2011)

Extrinsic Contribution and Instability Properties in Lead-Based and Lead-Free Piezoceramics
por: García, José Eduardo
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_ueg52bf847gp58mummkvrue8lk