Islet1 is a direct transcriptional target of the homeodomain transcription factor Shox2 and rescues the Shox2-mediated bradycardia

The heart’s rhythm is initiated and regulated by a group of specialized cells in the sinoatrial node (SAN), the primary pacemaker of the heart. Abnormalities in the development of the SAN can result in irregular heart rates (arrhythmias). Although several of the critical genes important for SAN form...

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Detalles Bibliográficos
Autores principales: Hoffmann, Sandra, Berger, Ina M., Glaser, Anne, Bacon, Claire, Li, Li, Gretz, Norbert, Steinbeisser, Herbert, Rottbauer, Wolfgang, Just, Steffen, Rappold, Gudrun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2013
Materias:
Original Contribution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597335/
https://www.ncbi.nlm.nih.gov/pubmed/23455426
http://dx.doi.org/10.1007/s00395-013-0339-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597335/
https://www.ncbi.nlm.nih.gov/pubmed/23455426
http://dx.doi.org/10.1007/s00395-013-0339-z

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