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A Conserved Upstream Motif Orchestrates Autonomous, Germline-Enriched Expression of Caenorhabditis elegans piRNAs

Piwi-interacting RNAs (piRNAs) fulfill a critical, conserved role in defending the genome against foreign genetic elements. In many organisms, piRNAs appear to be derived from processing of a long, polycistronic RNA precursor. Here, we establish that each Caenorhabditis elegans piRNA represents a ti...

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Detalles Bibliográficos
Autores principales: Billi, Allison C., Freeberg, Mallory A., Day, Amanda M., Chun, Sang Young, Khivansara, Vishal, Kim, John K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597512/
https://www.ncbi.nlm.nih.gov/pubmed/23516384
http://dx.doi.org/10.1371/journal.pgen.1003392