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Surveillance-Activated Defenses Block the ROS–Induced Mitochondrial Unfolded Protein Response

Disturbance of cellular functions results in the activation of stress-signaling pathways that aim at restoring homeostasis. We performed a genome-wide screen to identify components of the signal transduction of the mitochondrial unfolded protein response (UPR(mt)) to a nuclear chaperone promoter. We...

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Detalles Bibliográficos
Autores principales: Runkel, Eva D., Liu, Shu, Baumeister, Ralf, Schulze, Ekkehard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597513/
https://www.ncbi.nlm.nih.gov/pubmed/23516373
http://dx.doi.org/10.1371/journal.pgen.1003346