Heteroduplex DNA Position Defines the Roles of the Sgs1, Srs2, and Mph1 Helicases in Promoting Distinct Recombination Outcomes

The contributions of the Sgs1, Mph1, and Srs2 DNA helicases during mitotic double-strand break (DSB) repair in yeast were investigated using a gap-repair assay. A diverged chromosomal substrate was used as a repair template for the gapped plasmid, allowing mismatch-containing heteroduplex DNA (hDNA)...

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Detalles Bibliográficos
Autores principales: Mitchel, Katrina, Lehner, Kevin, Jinks-Robertson, Sue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597516/
https://www.ncbi.nlm.nih.gov/pubmed/23516370
http://dx.doi.org/10.1371/journal.pgen.1003340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597516/
https://www.ncbi.nlm.nih.gov/pubmed/23516370
http://dx.doi.org/10.1371/journal.pgen.1003340

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