Microhomology-Mediated Mechanisms Underlie Non-Recurrent Disease-Causing Microdeletions of the FOXL2 Gene or Its Regulatory Domain

Genomic disorders are often caused by recurrent copy number variations (CNVs), with nonallelic homologous recombination (NAHR) as the underlying mechanism. Recently, several microhomology-mediated repair mechanisms—such as microhomology-mediated end-joining (MMEJ), fork stalling and template switchi...

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Detalles Bibliográficos
Autores principales: Verdin, Hannah, D'haene, Barbara, Beysen, Diane, Novikova, Yana, Menten, Björn, Sante, Tom, Lapunzina, Pablo, Nevado, Julian, Carvalho, Claudia M. B., Lupski, James R., De Baere, Elfride
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597517/
https://www.ncbi.nlm.nih.gov/pubmed/23516377
http://dx.doi.org/10.1371/journal.pgen.1003358

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597517/
https://www.ncbi.nlm.nih.gov/pubmed/23516377
http://dx.doi.org/10.1371/journal.pgen.1003358

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