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RFECS: A Random-Forest Based Algorithm for Enhancer Identification from Chromatin State

Transcriptional enhancers play critical roles in regulation of gene expression, but their identification in the eukaryotic genome has been challenging. Recently, it was shown that enhancers in the mammalian genome are associated with characteristic histone modification patterns, which have been incr...

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Detalles Bibliográficos
Autores principales: Rajagopal, Nisha, Xie, Wei, Li, Yan, Wagner, Uli, Wang, Wei, Stamatoyannopoulos, John, Ernst, Jason, Kellis, Manolis, Ren, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597546/
https://www.ncbi.nlm.nih.gov/pubmed/23526891
http://dx.doi.org/10.1371/journal.pcbi.1002968