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RFECS: A Random-Forest Based Algorithm for Enhancer Identification from Chromatin State
Transcriptional enhancers play critical roles in regulation of gene expression, but their identification in the eukaryotic genome has been challenging. Recently, it was shown that enhancers in the mammalian genome are associated with characteristic histone modification patterns, which have been incr...
Autores principales: | Rajagopal, Nisha, Xie, Wei, Li, Yan, Wagner, Uli, Wang, Wei, Stamatoyannopoulos, John, Ernst, Jason, Kellis, Manolis, Ren, Bing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597546/ https://www.ncbi.nlm.nih.gov/pubmed/23526891 http://dx.doi.org/10.1371/journal.pcbi.1002968 |
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