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Functional Enhancement of AT1R Potency in the Presence of the TPαR Is Revealed by a Comprehensive 7TM Receptor Co-Expression Screen

BACKGROUND: Functional cross-talk between seven transmembrane (7TM) receptors can dramatically alter their pharmacological properties, both in vitro and in vivo. This represents an opportunity for the development of novel therapeutics that potentially target more specific biological effects while ca...

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Detalles Bibliográficos
Autores principales: Hansen, Jonas Tind, Lyngsø, Christina, Speerschneider, Tobias, Hansen, Pernille B. L., Galés, Céline, Weiner, David M., Sheikh, Søren P., Burstein, Ethan S., Hansen, Jakob Lerche
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597553/
https://www.ncbi.nlm.nih.gov/pubmed/23516570
http://dx.doi.org/10.1371/journal.pone.0058890