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Functional Enhancement of AT1R Potency in the Presence of the TPαR Is Revealed by a Comprehensive 7TM Receptor Co-Expression Screen
BACKGROUND: Functional cross-talk between seven transmembrane (7TM) receptors can dramatically alter their pharmacological properties, both in vitro and in vivo. This represents an opportunity for the development of novel therapeutics that potentially target more specific biological effects while ca...
Autores principales: | Hansen, Jonas Tind, Lyngsø, Christina, Speerschneider, Tobias, Hansen, Pernille B. L., Galés, Céline, Weiner, David M., Sheikh, Søren P., Burstein, Ethan S., Hansen, Jakob Lerche |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597553/ https://www.ncbi.nlm.nih.gov/pubmed/23516570 http://dx.doi.org/10.1371/journal.pone.0058890 |
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