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Protein Malnutrition Induces Bone Marrow Mesenchymal Stem Cells Commitment to Adipogenic Differentiation Leading to Hematopoietic Failure

Protein malnutrition (PM) results in pathological changes that are associated with peripheral leukopenia, bone marrow (BM) hypoplasia and alterations in the BM microenvironment leading to hematopoietic failure; however, the mechanisms involved are poorly understood. In this context, the BM mesenchym...

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Detalles Bibliográficos
Autores principales: Cunha, Mayara Caldas Ramos, Lima, Fabiana da Silva, Vinolo, Marco Aurélio Ramirez, Hastreiter, Araceli, Curi, Rui, Borelli, Primavera, Fock, Ricardo Ambrósio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597562/
https://www.ncbi.nlm.nih.gov/pubmed/23516566
http://dx.doi.org/10.1371/journal.pone.0058872