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Protein Malnutrition Induces Bone Marrow Mesenchymal Stem Cells Commitment to Adipogenic Differentiation Leading to Hematopoietic Failure
Protein malnutrition (PM) results in pathological changes that are associated with peripheral leukopenia, bone marrow (BM) hypoplasia and alterations in the BM microenvironment leading to hematopoietic failure; however, the mechanisms involved are poorly understood. In this context, the BM mesenchym...
Autores principales: | Cunha, Mayara Caldas Ramos, Lima, Fabiana da Silva, Vinolo, Marco Aurélio Ramirez, Hastreiter, Araceli, Curi, Rui, Borelli, Primavera, Fock, Ricardo Ambrósio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597562/ https://www.ncbi.nlm.nih.gov/pubmed/23516566 http://dx.doi.org/10.1371/journal.pone.0058872 |
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