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Microstructural White Matter Changes, Not Hippocampal Atrophy, Detect Early Amnestic Mild Cognitive Impairment

BACKGROUND: Alzheimer’s disease (AD) is generally considered to be characterized by pathology in gray matter of the brain, but convergent evidence suggests that white matter degradation also plays a vital role in its pathogenesis. The evolution of white matter deterioration and its relationship with...

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Detalles Bibliográficos
Autores principales: Zhuang, Lin, Sachdev, Perminder S., Trollor, Julian N., Reppermund, Simone, Kochan, Nicole A., Brodaty, Henry, Wen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597581/
https://www.ncbi.nlm.nih.gov/pubmed/23516569
http://dx.doi.org/10.1371/journal.pone.0058887