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Lack of Tryptophan Hydroxylase-1 in Mice Results in Gait Abnormalities

The role of peripheral serotonin in nervous system development is poorly understood. Tryptophan hydroxylase-1 (TPH1) is expressed by non-neuronal cells including enterochromaffin cells of the gut, mast cells and the pineal gland and is the rate-limiting enzyme involved in the biosynthesis of periphe...

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Detalles Bibliográficos
Autores principales: Suidan, Georgette L., Duerschmied, Daniel, Dillon, Gregory M., Vanderhorst, Veronique, Hampton, Thomas G., Wong, Siu Ling, Voorhees, Jaymie R., Wagner, Denisa D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597584/
https://www.ncbi.nlm.nih.gov/pubmed/23516593
http://dx.doi.org/10.1371/journal.pone.0059032