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Lack of Tryptophan Hydroxylase-1 in Mice Results in Gait Abnormalities
The role of peripheral serotonin in nervous system development is poorly understood. Tryptophan hydroxylase-1 (TPH1) is expressed by non-neuronal cells including enterochromaffin cells of the gut, mast cells and the pineal gland and is the rate-limiting enzyme involved in the biosynthesis of periphe...
Autores principales: | Suidan, Georgette L., Duerschmied, Daniel, Dillon, Gregory M., Vanderhorst, Veronique, Hampton, Thomas G., Wong, Siu Ling, Voorhees, Jaymie R., Wagner, Denisa D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597584/ https://www.ncbi.nlm.nih.gov/pubmed/23516593 http://dx.doi.org/10.1371/journal.pone.0059032 |
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